Molecular Formula | C19H20F3NO4 |
Molar Mass | 383.36 |
Density | 1.2100 |
Melting Point | 13°C |
Boling Point | bp0.05 167° |
Flash Point | 2°C |
Water Solubility | 536.6ug/L(temperature not stated) |
Appearance | neat |
Merck | 13,4142 |
pKa | 0.78±0.22(Predicted) |
Storage Condition | 0-6°C |
Physical and Chemical Properties | Colorless or light yellow oily liquid. Boiling point 167 ℃(6.65 × 10-3kPa), it can be miscible with methanol, propyl, cycloethyl ketone, hexane, xylene, chloroform, and its solubility in water is 2ppm. At 37 ℃, the properties were stable for 6 months. The preparation is brown liquid with a density of 0.998 at 20 ℃. There are two isomers in the chemical structure of pirfluoxazole, namely R-body (with herbicidal activity) and S-body (without herbicidal activity). In general stable preparations, the two isomers are each It accounts for half, and the R-body in the refined and separated preparation contains 90%, which is called Jingwenzide (SL-236-P, onecide-P), and its herbicidal activity is increased by about 2 times compared with stable killing. It can be stored in direct sunlight for 2 years without deterioration. Stable to ultraviolet light; However, it was rapidly hydrolyzed in moist soil with DT50<7d, while DT50 of fouaxifop- P was about 21d. Stable for more than 1 year at 25 ℃ and stable for 2 weeks at 50 ℃. |
Risk Codes | R61 - May cause harm to the unborn child R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. |
UN IDs | UN3082 9/PG 3 |
WGK Germany | 3 |
RTECS | UA3000000 |
HS Code | 29333990 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Herbicide | Pyrifluoxaolin is also known as fluoxazide, flupiram, and stable. Developed by the British Bu Neimen Company and the Japanese Ishihara Industrial Company in the same period in 1978. It is a selective stem and leaf treatment herbicide for gramineous weeds in dicotyledonous crops. It has a strong killing effect on annual gramineous weeds, and also has a good control effect on perennial gramineous weeds. It is safe for broad-leaved crops and ineffective for dicotyledonous weeds. Weeds are mainly absorbed and conducted through stems and leaves, and roots can also absorb and conduct. Inhibit cell division, hinder energy transfer, destroy photosynthesis, and gradually kill weeds. Gramineae weeds stopped growing within 48 hours after application. Tillering nodes and growing points turned brown in 4~7 days. Heart leaves and other leaves successively lost green and yellow, and gradually died. It is difficult to kill the grass weeds without heading, but it is manifested as short above ground, short root, black root tip and unable to extend, and small seed setting. The residual period in the soil is 1~2 months, and the mobility is 1~2cm. The amount of soil treatment is 2~4 times higher than that of stem and leaf treatment, so it is generally only treated by spray treatment of stem and leaf. |
toxicity | pyrifloxazole is a low-toxic herbicide. The acute oral LD50 of the original drug was 3328mg/kg in rats and more than 2420mg/kg in mice. No chronic toxic effects were found in mice and rats. The undiluted preparation has a moderate irritation to the skin and eyes of rabbits, and the diluted liquid medicine is slightly irritated. It has no irritating effect on human skin and is relatively safe for bees, birds, earthworms and soil microorganisms. But it is moderately toxic to fish. At 15 ℃, LC50(96 hours, red frog fish is 1.37mg/l. There are very few residues of pyrifluproxine in crops. The maximum allowable residue (US) is 1 mg/kg in soybean and 2 mg/kg in soybean oil. The daily allowable intake (DI) of human body is 0.25 mg/kg. |
control object | mainly used in broad-leaved crops, such as cotton, soybean, peanut, rape, mint, sugar beet, sweet potato, potato, watermelon, flax, broad-leaved vegetables, tobacco, peas, orchards, vineyards, rubber plantations and vegetable fields to control annual and perennial gramineous weeds, for example, look at Mai Niang, Setaria, Barnyard, Matang, Beushion, Wild Oats, Reed, Stone Grass, Bermudagrass, Cricket Grass, Grape Ice Grass, Perennial Sorghum, etc. However, gramineous weeds such as Qianjinzi and Poa pratensis have certain resistance to pyrifloxopyrin. |
precautions | (1) when controlling weeds of grasses in broad-leaved crops with pyrifloxazole, liquid medicine should be prevented from drifting onto grasses to avoid phytotoxicity. At the same time, the used and stable equipment should be thoroughly cleaned before it can be used for application of gramineous crops. (2) When the air humidity and the land humidity are high, it is beneficial to the absorption and transportation of weeds to the stable killing, and the drug effect is easy to play. When applying pesticide under high temperature and drought conditions, the weed stems and leaves cannot fully absorb the pesticide, and the efficacy will be affected to a certain extent. At this time, the dosage should be appropriately increased. (3) It can only control gramineous weeds and is ineffective against broadleaf weeds. Therefore, the control of broad-leaved weeds should be strengthened with fields that can be weeded steadily. (4) It can be mixed with Huwei, but it cannot be mixed with grass. Weed burning should be mixed with caution. (5) This product is a flammable liquid, and the fire source should be avoided during transportation. |
use | pyrifluproxine is a herbicide for controlling gramineous weeds and selective post-bud. It is used in cotton, soybean, rape and other fields to control annual and perennial weeds with remarkable effect. The oral LD50 was 3000mg/kg for rats, 1490mg/kg for male mice and 1770mg/kg for female mice. |
production method | there are mainly the following two methods. 1. The corresponding hydroxy ether is prepared by the reaction of 2-chloro-5-trifluoromethylpyridine and hydroquinone in alkaline medium by etherification method, and then condensed with α-butyl chloropropionate. 2. The post-etherification method is firstly obtained by condensation of hydroquinone and α-butyl bromopropionate, and then the obtained product is fluorinated with 2-chloro-5-trichloromethylpyridine. Both of the above methods require the intermediate 2-chloro-5-trifluoromethylpyridine, which can be obtained by fluorination of 2-chloro-5-trichloromethylpyridine. |
category | pesticide |
toxicity classification | poisoning |
acute toxicity | oral-rat LD50: 2910 mg/kg; Oral-mouse LD50: 1490 mg/kg |
flammability hazard characteristics | Combustion produces toxic nitrogen oxides and fluoride gases |
storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials storage and transportation |
fire extinguishing agent | dry powder, foam, sand |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |